The skin is a platform composed of "neuro-hormones". All it takes is a sudden stress for the skin to activate its transmitters, the sebocytes, and for them to induce a response by increasing the quantity of sebum. We talk to our skin, it expresses in pain what we cannot say with words. This is why it is essential to integrate the relationship between the body and the mind in the management of acne and its impact on quality of life, self-image, self-esteem and self-confidence. The skin is a platform composed of "neurohormones".